Tejasvini Neve, Vijaya Vichare, Manasi Rokade, S.N. Dhole
Tejasvini Neve*, Vijaya Vichare, Manasi Rokade, S.N. Dhole
PES Modern College of Pharmacy (For Ladies) Moshi, Savitribai Phule University, Pune, Maharashtra, India.
Volume - 13,
Issue - 3,
Year - 2023
A simple, rapid and eco-friendly UV spectroscopic method was developed for the estimation of Adapalene along with Phenoxyethanol for laboratory purpose. Bulk drug and marketed formulation both are analyzed and validated by this method. Tetrahydrofuran was selected for the solubility of Adapalene and Phenoxyethanol as per solubility profile. Wavelength selected for Adapalene and Phenoxyethanol was 325nm and 269nm respectively. In the proposed method, adapalene and phenoxyethanol follows linearity in the concentration range 1-5µg/mL and 2.5-12.5µg/mL with a correlation coefficient 0.999 and 0.998 respectively. Proposed method was statistically validated as per ICH guidelines and by recovery studies. The standard deviation was found to be less than 2, which showed excellent precision and accuracy.
Cite this article:
Tejasvini Neve, Vijaya Vichare, Manasi Rokade, S.N. Dhole. Simultaneous Estimation of Adapalene from Marketed Gel Formulation along with the Preservative Phenoxyethanol by UV- Visible Spectroscopy. Asian Journal of Pharmaceutical Research. 2023; 13(3):206-9. doi: 10.52711/2231-5691.2023.00039
Tejasvini Neve, Vijaya Vichare, Manasi Rokade, S.N. Dhole. Simultaneous Estimation of Adapalene from Marketed Gel Formulation along with the Preservative Phenoxyethanol by UV- Visible Spectroscopy. Asian Journal of Pharmaceutical Research. 2023; 13(3):206-9. doi: 10.52711/2231-5691.2023.00039 Available on: https://www.asianjpr.com/AbstractView.aspx?PID=2023-13-3-13
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