Author(s):
Roshani Bhalerao*, Dinesh Rishipathak, Pavan Udavant, Sanjay Kshirsagar
Email(s):
Email ID Not Available
DOI:
10.5958/2231-5691.2017.00041.7 
Address:
Roshani Bhalerao*, Dinesh Rishipathak, Pavan Udavant, Sanjay Kshirsagar
MET’S Institute of Pharmacy, Bhujbal Knowledge City, Adgaon, Nashik-422003,
Savitribai Phule Pune University, India
*Corresponding Author
Published In:
Volume - 7,
Issue - 4,
Year - 2017
ABSTRACT:
The aim of study was to synthesize a new series of Thiazolidinedione. Thiazolidinedione or glitziness forms a significant class of drug which exhibit biological activities ranging from antidiabetic, antiinflamatory, antibacterial, antifungal, antiviral, and anti-cancer. In the present study reported a systematic synthesis of thiazolidinedione. A new series of 2,4-thiazolidinedione based derivative have been synthesize by condensation of. The structure of these compounds were establish by IR and 1H NMR. These new compound (C1-C4) were evaluated for their antidiabetic activity on albino rat. Most of compound shows significant antidiabetic activity when compare with standard drug metformin.
Cite this article:
Roshani Bhalerao*, Dinesh Rishipathak, Pavan Udavant, Sanjay Kshirsagar. Synthesis and Evaluation of Antidiabetic Activity of Few 5-(4-(5-Substitutedphenyl)-1,3,4-Oxadiazlole-2-Yl) Methoxy)Benzylidene) Thiazolidine 2,4-Dione Derivatives. Asian J. Pharm. Res. 2017; 7(4): 261-264. doi: 10.5958/2231-5691.2017.00041.7
Cite(Electronic):
Roshani Bhalerao*, Dinesh Rishipathak, Pavan Udavant, Sanjay Kshirsagar. Synthesis and Evaluation of Antidiabetic Activity of Few 5-(4-(5-Substitutedphenyl)-1,3,4-Oxadiazlole-2-Yl) Methoxy)Benzylidene) Thiazolidine 2,4-Dione Derivatives. Asian J. Pharm. Res. 2017; 7(4): 261-264. doi: 10.5958/2231-5691.2017.00041.7 Available on: https://www.asianjpr.com/AbstractView.aspx?PID=2017-7-4-9