Computational approach is used to identify the binding region of alpha-enolase over cell-surface protein of neutrophil. The product of alpha-enolase gene binds the one of the cell surface protein of neutrophil known as myoblast. After the binding on myoblast, neutrophil structure gets change and mobilized chromatin fibers came out to eliminate pathogen though NETosis. Thus, over study revealed that alpha-enolase of Streptococcus Pneumoniae is one of the major factor in inducing NETs during innate immune response.
Cite this article:
Muhammad Hassan, Atif Amin Baig. Induction of Neutrophil Extracellular Traps (NETs) by Alpha-Enolase of Streptococcus pneumoniae. Asian Journal of Pharmaceutical Research. 2021; 11(2):95-6. doi: 10.52711/2231-5691.2021.00018
Muhammad Hassan, Atif Amin Baig. Induction of Neutrophil Extracellular Traps (NETs) by Alpha-Enolase of Streptococcus pneumoniae. Asian Journal of Pharmaceutical Research. 2021; 11(2):95-6. doi: 10.52711/2231-5691.2021.00018 Available on: https://www.asianjpr.com/AbstractView.aspx?PID=2021-11-2-4
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