Author(s):
Sanguni G, Thilaga G, Paustinaancy R, Gowri M
Email(s):
sriadit.gowrisuresh@gmail.com
DOI:
10.52711/2231-5691.2025.00045 
Address:
Sanguni G1, Thilaga G1, Paustinaancy R1, Gowri M2*
1Departmant of Chemistry, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore - 641043, Tamil Nadu, India.
2Associate Professor, Department of Chemistry, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore - 641043, Tamil Nadu, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 3,
Year - 2025
ABSTRACT:
The pharmacological activities of Schiff bases generated from isatin include antibacterial, antifungal, anti-inflammatory, antiviral, anticancer, antioxidant, anticonvulsant, analgesic, anti-tubercular, and anti-depression. Because of these activities, they find numerous applications in various fields, particularly medical and pharmaceutical. Some have the most potent antioxidant activity, protecting cells against free radicals linked to diseases like cancer, heart disease, stroke, inflammation, and aging, making antioxidant activity more significant. As a result, the importance of antioxidants in pharmacology and medicine is expanding. The reagents 2, 2-Diphenyl-1-picrylhydrazyl (DPPH), CUPRAC and 2, 2'-Azino-bis (3-ethyl benzothiazoline-6-sulfonic acid) are used to determine the antioxidant ability of the naturally occurring and synthetic compounds. Standard antioxidants such as Quercetin, Trolox, and L-ascorbic acid compare a compound's antioxidant activity. The current review summarises the antioxidant activity of isatin's Schiff base derivatives and their metal complexes.
Cite this article:
Sanguni G, Thilaga G, Paustinaancy R, Gowri M. Antioxidant Activity of Isatin-Schiff Base Scaffold: A Review. Asian Journal of Pharmaceutical Research. 2025; 15(3):287-4. doi: 10.52711/2231-5691.2025.00045
Cite(Electronic):
Sanguni G, Thilaga G, Paustinaancy R, Gowri M. Antioxidant Activity of Isatin-Schiff Base Scaffold: A Review. Asian Journal of Pharmaceutical Research. 2025; 15(3):287-4. doi: 10.52711/2231-5691.2025.00045 Available on: https://www.asianjpr.com/AbstractView.aspx?PID=2025-15-3-9
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