ABSTRACT:
With several setbacks, scientists continue to pursue an appropriate medicine or vaccine in order to combat the current epidemic. At one point, the use of combination medications is possibly just the correct way to find successful coronavirus therapy.
Cite this article:
Ali Adel Dawood. Using Remdesivir and Dexamethasone for Treatment of SARS-CoV-2 Shortens the patient's stay in the Hospital. Asian Journal of Pharmaceutical Research. 2021; 11(2):138-0. doi: 10.52711/2231-5691.2021.00026
Cite(Electronic):
Ali Adel Dawood. Using Remdesivir and Dexamethasone for Treatment of SARS-CoV-2 Shortens the patient's stay in the Hospital. Asian Journal of Pharmaceutical Research. 2021; 11(2):138-0. doi: 10.52711/2231-5691.2021.00026 Available on: https://www.asianjpr.com/AbstractView.aspx?PID=2021-11-2-12
REFERENCES:
1. Bunim JJ, Black RL, Lutwak L, Peterson RE, Whedon GD. Studies on dexamethasone, a new synthetic steroid, in rheurheumatoid arthritis: a preliminary report; adrenal cortical, metabolic and early clinical effects. Arthritis Rheum. 1958;1(4): 313-31. http://doi:10.1002/art.1780010404. [PubMed:13560344].
2. Horby P, Lim W, and Mafham M et al. Effect of Dexamethasone in Hospitalized Patients with COVID-19: Preliminary Report. medRXiv. 2020; https://doi.org/10.1101/2020.06.22.20137273.
3. WHO. WHO welcomes preliminary results about dexamethasone use in treating critically ill COVID-19 patients.2020; June, 16. https://www.who.int/news-room/detail/16-06-2020-who-welcomes-preliminary-results-about-dexamethasone-use-in-treating-critically-ill-covid-19-patients.
4. Eastman RT, Roth JS, Brimacombe KR, et al. Remdesivir: a review of its discovery and development leading to emergency use authorization for treatment of COVID-19. ACS Cent Sci. 2020;6: 672–683. http://doi:10.1021/acscentsci.0c00489.
5. Warren TK, Jordan R, and et al. Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys. Nature. 2016;17;531(7594):381-5. http://doi:10.1038/nature17180. [PubMed:26934220].
6. Sheahan TP, Sims AC, and Graham RL et al. Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Sci Transl Med. 2017;28; 9(396). pii: 9/396/eaal3653. http://doi:10.1126/scitranslmed.aal3653. [PubMed:28659436].
7. Hashemian SM. A Review on Remdesivir: A Possible Promising Agent for the Treatment of COVID-19. Dovepress. 2020;14: 3215—3222. https://doi.org/10.2147/DDDT.S261154.
8. Gonzales-Zamora J, Quiroz T, and Vega A. Successful treatment with Remdesivir and corticosteroids in a patient with COVID-19-associated pneumonia: A case report. MedWave. 2020; 20(7):e7998. https://doi:10.5867/medwave.2020.07.7998.
9. U.S. Food and Drug Administration. Coronavirus (COVID-19) Update: FDA Issues Emergency Use Authorization for Potential COVID-19 Treatment. 2020; May:1. https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-issues-emergency-use-authorization-potential-covid-19-treatment.
10. Sonia M, Prem S, Subhash W, and Tarunika B. Worldwide spread of COVID-19 Pandemic and risk factors among Co-morbid conditions especially Diabetes Mellitus in India. Research J. Pharm. and Tech 2020; 13(5): 2530-2532.
11. Thoutreddy R, Gullapudi M, and Bonepally R. Formulation and Evaluation of Dexamethasone Loaded Cubosomes. Research J. Pharm. and Tech 2020; 13(2): 709-714.
12. Shaikh S. Effect of Aegle marmelose Linn. Leaves in Dexamethasone Induced Insulin Resistance Diabetic Mice. Research J. Pharm. and Tech. 8(3): Mar., 2015; Page 270-275.
13. Wang Y, Zhang D, and Du G, et al. Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial. Lancet 2020; 395: 1569–78. https://doi.org/10.1016/S0140-6736(20)31022-9.
14. Beigel J, Tomashek K, and Dodd L, et al. Remdesivir for the Treatment of Covid-19- Preliminary Report. New Eng J Med. 2020; May. http://doi:10.1056/NEJMoa2007764.
15. B. V. Naresh. A Review of the 2019 Novel Coronavirus (COVID-19) Pandemic. Asian J. Pharm. Res. 2020; 10(3):233-238.
16. Dawood A. Should we worry that the COVID-19 could be transmitted with the semen? As J Pharm Res. 2020; 10(4): 319-320. https://doi:10.5958/2231-5691.2020.00054.4.
17. Dawood A, Altobje M. Inhibition of N-linked Glycosylation by Tunicamycin May Contribute to The Treatment of SARS-CoV-2. Mic Path. 2020; 149:104586. https://doi.org/10.1016/j.micpath.2020.104586.