Author(s): Achal H. Yelne*, Yashwant G. Jadhav

Email(s): achalyelane0503@gmail.com

DOI: 10.52711/2231-5691.2024.00019   

Address: Achal H. Yelne*, Yashwant G. Jadhav
Department of Pharmaceutics, P.R. Pote Patil College of Pharmacy, Amravati, Maharashtra, India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2024


ABSTRACT:
Numerous herbal plants play a crucial role in diverse traditional medicinal systems for treating various human diseases. One such plant, Lagenaria siceraria, has a rich history of utilization across different traditional medical systems. This plant contains a wide array of phytochemical constituents including triterpenoids, cucurbitacins, flavones, vitamin B, C-glycosides, beta glycosides, and a notable amount of ascorbic acid in its fruits. Notably, research has indicated that the fruit exhibits cardioprotective properties, while the leaves showcase antioxidant activity. The plant has been extensively studied for its pharmacological effects, encompassing antioxidant, cardioprotective, diuretic, immunomodulatory, hepatoprotective, lipid peroxidation, and anti-inflammatory activities. Although Lagenaria siceraria is cultivated on a limited scale in various regions of India, comprehensive information on its various aspects remains scarce. This review aims to address this gap by providing a consolidated overview of the plant's characteristics and potential medicinal properties.


Cite this article:
Achal H. Yelne, Yashwant G. Jadhav. Preparation, Evaluation and Comparison of Marketed Formulation of Bottle Gourd Churna of Plant (Lagenaria siceraria). Asian Journal of Pharmaceutical Research. 2024; 14(2):114-0. doi: 10.52711/2231-5691.2024.00019

Cite(Electronic):
Achal H. Yelne, Yashwant G. Jadhav. Preparation, Evaluation and Comparison of Marketed Formulation of Bottle Gourd Churna of Plant (Lagenaria siceraria). Asian Journal of Pharmaceutical Research. 2024; 14(2):114-0. doi: 10.52711/2231-5691.2024.00019   Available on: https://www.asianjpr.com/AbstractView.aspx?PID=2024-14-2-4


REFERENCES:
1.    Hetal J. Gorasiya, Archana paranjape, Krishna Murti. Pharmacognostic and pharmacological profile of Lagenaria siceraria (MOLINA) standley: a review. 2011: 317-324.
2.    Busuioc, A. C., Botezatu, A.-V. D., Furdui, B., Vinatoru, C., Maggi, F., Caprioli, G., and Dinica, R.-M. Comparative Study of the Chemical Compositions and Antioxidant Activities of Fresh Juices from Romanian Cucurbitaceae Varieties. Molecules. 2020; 25(22): 5468. https://doi.org/10.3390/molecules25225468
3.    Ahmed, D., Fatima, M., and Saeed, S. Phenolic and flavonoid contents and anti-oxidative potential of epicarp and mesocarp of Lagenaria siceraria fruit: a comparative study. Asian Pacific journal of tropical medicine. 2014; 7S1: S249–S255. https://doi.org/10.1016/S1995-7645(14)60241-8
4.    Shah, B., Seth, A., and Desai, R. Phytopharmacological Profile of Lagenaria siceraria: A Review. Asian Journal of Plant Sciences. 2010; 9(3): 152-157. https://doi.org/10.3923/ajps.2010.152.157
5.    Hanif, Rumeza and Iqbal, Zafar and Iqbal, Mudassar and Hanif, Shaheena and Rasheed, Masooma. Use of vegetables as nutritional food: Role in human health. J. Agric. Biol. Sci. 2006; 1.
6.    Majumdar, T.K. and Vasudish, C.R. and Premavalli, Bawa, Amarinder. Preservation of functional vegetable juice-ashgourd juice and ashgourd-pudina blended juice. 2009; 36: 48-50.
7.    Deshpande, J. R., Choudhari, A. A., Mishra, M. R., Meghre, V. S., Wadodkar, S. G., and Dorle, A. K. Beneficial effects of Lagenaria siceraria (Mol.) Standley fruit epicarp in animal models. Indian journal of experimental biology. 2008; 46(4): 234–242.
8.    Mariod, Abdalbasit and Ahmed, Yousif and Matthäus, B. and  Khaleel, Galaledin and  Elkhedir, Abdeen and Gabra, Aied and Abdelwahab, Siddig. A Comparative Study of the Properties of Six Sudanese Cucurbit Seeds and Seed Oils. Journal of the American Oil Chemists' Society. 2009; 86: 1181-1188. 10.1007/s11746-009-1459-3.
9.    Kothari, V., Gupta, A., and Naraniwal, M. Comparative Study of Various Methods for Extraction of Antioxidant and Antibacterial Compounds from Plant Seeds. Journal of Natural Remedies. 2012; 12(2): 162–173. https://doi.org/10.18311/jnr/2012/271
10.    Gangwal, A. Isolation and immunomodulatory activity of phytoconstituents of Lagenaria siceraria fruits. 2010
11.    Prajapati, R. P., Kalariya, M., Parmar, S. K., and Sheth, N. R.  Phytochemical and pharmacological review of Lagenaria sicereria. Journal of Ayurveda and Integrative Medicine. 2010; 1(4): 266–272. https://doi.org/10.4103/0975-9476.74431
12.    Ghule, B. V., Ghante, M. H., Saoji, A. N., and Yeole, P. G. Hypolipidemic and antihyperlipidemic effects of Lagenaria siceraria (Mol.) fruit extracts. Indian Journal of Experimental Biology. 2006; 44(11): 905–909.
13.    Ghule, B., Ghante, M., Yeole, P., and Saoji, A. Diuretic activity of lagenaria siceraria fruit extracts in rats. Indian Journal of Pharmaceutical Sciences. 2007; 69(6): 817. https://doi.org/10.4103/0250-474x.39441
14.    C. Gopalan, B. V. R. Shastri and S. C. Balasubramanian, Nutritive Value of Indian Foods. National Institute of Nutrition, Hyderabad, 1985.
15.    Ghule, B., Ghante, M., Yeole, P., and Saoji, A. Diuretic activity of Lagenaria siceraria fruit extracts in rats. Indian Journal of Pharmaceutical Sciences. 2007; 69(6): 817. https://doi.org/10.4103/0250-474x.39441
16.    Morimoto, Y., Gikungu, M.W., and Maundu, P. Pollinators of the bottle gourd (Lagenaria siceraria) observed in Kenya. International Journal of Tropical Insect Science. 2004; 24: 79-86.
17.    Heiser, C. The gourd book. University of Oklahoma Press. 1993
18.    Rakesh P. Prajapati, Manisha V. Kalariya, Sachin K. Parmar. Evaluation of Anti-Psychotic potential of Phytocompound rich Fractions of Methanolic extract of Lagenaria siceraria (Bottle Gourd) fruits in Murine Models of Schizophrenia. Research Journal of Pharmacy and Technology. 2021; 14(10): 5242-8. doi: 10.52711/0974-360X.2021.00913
19.    Ganesh G. Dhakad, Kaveri P. Tambe, Sangita P. Shirsat, Neha R. Jaiswal. Review on Study of Bottle Gourd on Human Health. Research Journal of Pharmacology and Pharmacodynamics. 2022; 14(3): 174-8. doi: 10.52711/2321-5836.2022.00030
20.    N. Sampath Kumar, G. Madhurambal. Cucurbitacin Glycosides from the fruits of Citrullus colocynthis (L). Research J. Pharmacognosy and Phytochemistry. 2010; 2(3): 200-202.
21.    Manal Darwish, Mohamed Isam Hasan Agha, Soufi Barkil, Oussama Mansour. Separating and determining the effective compounds percentage in Ecballium elaterium L. Cucurbitacins Syria. Research J. Pharm. and Tech. 2015; 8(7): 829-835. doi: 10.5958/0974-360X.2015.00135.3
22.    Ganesh G. Dhakad, Kaveri P. Tambe, Sangita P. Shirsat, Neha R. Jaiswal. Review on Study of Bottle Gourd on Human Health. Research Journal of Topical and Cosmetic Sciences. 2022; 13(1): 44-8
23.    Dhananjay Babanrao Deshmukh, Mahesh Ramrao Sherkar. Evaluation of In Vivo Analgesic and Anti-Inflammatory Activity of Ethanolic Extract of Medicinal Plant -Lagenaria siceraria. Asian J. Pharm. Tech. 2019; 9(2): 75-78.
24.    Dahikar S. B. In Vitro Antimicrobial Activity of Fruit Extracts of Lagenaria Siceraria (Mol.). Res. J. Pharmacognosy and Phytochem. 2018; 10(2): 183-186.
25.    Tarange R G, Kharat J S, Jedage H D, Manjunath K P. Phytochemical screening for Antioxidant and Antifungal activity of Lagenaria siceraria (Molina) Standl. leaf extract. Res. J. Pharmacognosy and Phytochem. 2019; 11(3): 155-159.
26.    Ganesh G. Dhakad, Megha S. Nannaware, Gauri V. Wagh, Abhijit V. Shrirao, N.I. Kochar, A.V. Chandewar. Review on medicinal Use of Pumpkin Seed on Human Health. Research Journal of Pharmacology and Pharmacodynamics.2023; 15(2): 59-5.
27.    Hala Juha, Fida Amali. Effect of Boiling on Carotenoids content of Pumpkin available in Damascus, Syria. Research Journal of Pharmacy and Technology. 2021; 14(11): 5642-6.


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